An easy way to figure out how far you need to go is tweaking it at idle. Adjust your idle flow first, then adjust the rest of the tables accordingly. Drive around town, a few highway speeds to relearn your trims again after you do.
Oh, and after every tweak, I reset the trims, and drive again. Do all of this without going into PE mode so that you don't lean out.
Histograms are the greatest thing about HPT IMO.