As basically as possible. Connect the yellow (constant power) from the radio to the yellow on the harness. Do the same with the reds (switch power) to the red on the harness . And the black (ground) to black.
The white and white/black ..... grey and grey/black ..... green and green/black.... and purple and purple/black are your speaker wires. Connect those wires from the radio to the matching wires on the harness.
The blue/white wire from the radio is an amp turn on lead. If you do not have an amp, capped that line off. The orange and orange/white wires are just illumination wires. If you want, you can connect the orange/white from the radio to the wire (will be the orange or orange/white) labeled "dimmer"... or you can just cap those off as the radio should have an independent dimming control
The brown wires are for a mute and aftermarket navigation units and onstar volume control. You can cap those off.
Blue/pink, green (from the 14 pin harness) and green purple are also for navigation, so you can cap those off as well.
That should do it...if Im missing any wires let me know.