I removed mine when I did my headers and left them off. I have considerably more room to work with now. It also only takes me 10 minutes to change out all 6 plugs.
As said though, the first time is going to be a pain because the original plug wire boots will be stuck to the plugs. Twisting them really hard will help to break the hold they have, and you may need to use a set of pliers for pulling them off as extra leverage.