Im thinking its one of three things
1. Bad head unit
2. Remote line from your head unit to your amp has a short
3. A bad speaker
I would just connect the power and ground ( Yellow, red and black wires )to the head unit and see if it still blows fuses. That will eliminate 2 and 3 and point you to #1, if the fuse pops. If it doesnt pop, connect the remote line and check to see if the fuse blows. If it doesnt, connect one speaker at a time and check for the blown fuse.
**Edit: Is the amp for the highs and mids....or subs?
