I ran into this before and had a mechanic replace it. He actually couldnt get the fuse box opened all the way and had to pull a few things to get it out - it worked for a few months but now doesnt. I have a feeling that whatever mechanism turns off the defogger to ensure overheating is not working and hence the fuse/relay burnt out again. I believe this happened during the winter when it was -10 degrees I ran the remote start for 20 mins with no frost on the back window to warm the car up.
In this past post you can see the pictures of the 'fuse box':
http://www.grandprixforums.net/threa...-Defogger-Fuse
The defogger fuse/relay is located behind the fuses you see in the picture. There is some way opening it up but its not apparent whats holding these together to get to the defogger fuse.