could be possible there are several different issues. when i read your vibration issues at 45 mph and the clunk when you turn hard i thought it could be a bad cv joint. that wouldn't account for the tire wear so that could be bad alignment, bad control arms, bad hub, bad tie rods (could be the clunk as well), even the steering rack can clunk if its bad. all those things can cause bad alignment or the car not being able to hold an alignment which will eat the tires up.