Could be a cracked head gasket. Start it up and check for a hissing noise by cylinder 5. It could also be a plugged injector so you could try replacing that. It MIGHT help to run some of that bottled injector cleaner crap through a tank of gas. I've never used the stuff, I always figured it was a gimmick. It could potentially be a cheap fix, but I'd wait and see what others think.