someone on CGP posted under the pcm and tuning about tuning for 60# and said he felt that his trans/converter was acting up.
Some maf tricks and such will cause this (if you are running a AFC/modded maf on 42# injectors, you may find issues).

The problem most people have with big injectors is the fact that they are trying to run a factory maf file on it for some reason... but you really need to be using a matt m maf / afc or something that moves your maf curve back within "stock range" and skew your injector table significantly.

I have 105# injectors in my car and my IFR values are around 150.... when they should really be around 60 or something, all because of my AFC pulling out 20%.