Looking at the Impala forums I found more of them having this issue. If it is all doors not working with the switch or the fob it looks to be a relay issue. There is one relay for locking and one for unlocking. I am going to try and get a new Relay first and try that.
Right now though I am trying to find out where the relay is located at on this car. I am finding mixed on the impala it is either by the passanger side fuse box or by the drivers side parking brake. I am not sure what one.