Ran like a champ on my PC, day after it launched. No issues to be had, save for some of the cutscenes where you have to hit a button before you die, but that's just because I'm half retarded.
Custom loop will always be pricier than a closed loop (like my little H80) The loop im building is probably going to be close to $550, but the tradeoff for noise and overclocking potential is well worth it.