not really, the pcm runs the car much better then the old days, tells you when theres a problem, then leads you to the cause.
i do miss the old days of timing lights and re jetting carbs, but the new is here aint it lol
the thing is if one sensor goes bad, the rest suffer due to no communication with each other. mpg drop, performance is also lost most of the time. depending on the code that pops up.
tuning is way easier these days, if you know how to do it. a few clicks of a mouse and you can play with your timing, fuel and so on.