You can use anti seize on the plug threads if you want. Unless you plan on leaving the plugs in for years, I wouldn't worry about the anti seize with iron heads.
You will want to put a little dielectric grease on the inside of the plug boots so the DO come off easier the next time around.
Also if you take off the black tubular alternator bracket off and leave it off, changing the plugs the next time without rocking the engine will be much easier.
What out for the manifold heatshields. They have no problem cutting your hands when you least expect it.
Headers and PRJ wires make changing plugs easier too.![]()