Of course... I actually have the Metra harness to power the HU left the monsoon amp in place. I split the RCA wires from the HU to the monsoon amp and to my four channel amp, diconnected all the speakers from the Monsoon and ran all new wiring from each speaker back to the four channel...the only thing on the monsoon amp is the Center channel speaker (dash). May not be the most innovative approach but it works flawlessly. Its a good idea tho, if you have a HU that has 4 volt preouts so when u split the RCA's you dont have to worry about distortion. Wish i knew how to make my own mono channel with my 4 channel because id like to have a bit more power coming out of that speaker but oh well...