Why did you replace the fuel pressure regulator???? If you were running rich I would have considered it, but it seems like that would be a completely random thing to replace when you have a misfire.... I mean check your plugs/wires/coils before you get that carried away.
What sort of crack are you smoking? I have never even seen a GM car with a fuel pressure sensor, let alone one that would have a code thrown for one... P1250 is an evap code, probably related to the gas cap being loose or something else screwed up with one of the solenoids....The P1250 was the FPR which you replace.
There are very few cases that people actually get the correct SC coils it seems like...I do have cheap coils though, I replaced them earlier this year.